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Ficlatuzumab
Ficlatuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target hepatocyte growth factor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Squamous cell carcinoma of head and neckD00007719521———3
Non-small-cell lung carcinomaD00228912———2
Myeloid leukemia acuteD015470C92.011———2
Head and neck neoplasmsD006258—1———1
Squamous cell carcinomaD002294—1———1
Oropharyngeal neoplasmsD009959—1———1
Lung neoplasmsD008175C34.9011———1
Respiratory tract neoplasmsD012142EFO_0003853D1411———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C801————1
Multiple myelomaD009101C90.01————1
LymphomaD008223C85.91————1
Pancreatic neoplasmsD010190EFO_0003860C251————1
GlioblastomaD005909EFO_00005151————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameFICLATUZUMAB
INNficlatuzumab
Description
Ficlatuzumab (humanized mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1174900-84-5
RxCUI—
ChEMBL IDCHEMBL1743018
ChEBI ID—
PubChem CID—
DrugBankDB11680
UNII ID77E89833TG (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
HGF
HGF
Organism
Homo sapiens
Gene name
HGF
Gene synonyms
HPTA
NCBI Gene ID
3082
Protein name
hepatocyte growth factor
Protein synonyms
fibroblast-derived tumor cytotoxic factor, hepatocyte growth factor (hepapoietin A; scatter factor), Hepatopoietin-A, lung fibroblast-derived mitogen, Scatter factor, SF
Uniprot ID
Q9UDU6
Mouse ortholog
Hgf (15234)
hepatocyte growth factor (Q6LBE6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 242 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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60 adverse events reported
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