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Etretinate
Tegison (etretinate) is a small molecule pharmaceutical. Etretinate was first approved as Tegison on 1986-09-30. It is used to treat psoriasis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Etretinate
Tradename
Company
Number
Date
Products
TEGISONRocheN-019369 DISCN1986-09-30
2 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
psoriasisEFO_0000676D011565L40
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
D05: Antipsoriatics
D05B: Antipsoriatics for systemic use
D05BB: Retinoids for treatment of psoriasis
D05BB01: Etretinate
HCPCS
No data
Clinical
Clinical Trials
82 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ContraceptionD003267254141338
HivD006678O98.71326
Hiv infectionsD015658EFO_0000764B201225
Bacterial vaginosisD016585EFO_000393233
Breast feedingD001942123
Drug interactionsD004347112
Postcoital contraceptionD044363112
EndometriosisD004715EFO_0001065N801112
Sickle cell anemiaD000755EFO_0000697D5722
Polycystic ovary syndromeD011085EFO_0000660E28.211
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Contraception behaviorD003268123
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DysmenorrheaD004412HP_0100607N94.622
Prostatic hyperplasiaD011470EFO_0000284N4011
Uterine hemorrhageD01459211
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hormonal contraceptionD00008028222
PregnancyD011247EFO_0002950Z33.122
PharmacokineticsD01059911
Opioid-related disordersD009293EFO_0005611F1111
Sexual behaviorD01272511
MenorrhagiaD008595N92.011
Weights and measuresD01489411
Therapeutic abortionD00003211
Induced abortionD00002811
InfertilityD007246EFO_000054511
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameETRETINATE
INNetretinate
Description
Etretinate is a retinoid, an enoate ester and an ethyl ester. It has a role as a keratolytic drug.
Classification
Small molecule
Drug classretinol derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOC(=O)/C=C(C)/C=C/C=C(C)/C=C/c1c(C)cc(OC)c(C)c1C
Identifiers
PDB
CAS-ID54350-48-0
RxCUI4182
ChEMBL IDCHEMBL464
ChEBI ID4913
PubChem CID5282375
DrugBankDB00926
UNII ID65M2UDR9AG (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,146 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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70,005 adverse events reported
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