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Etonogestrel
Nexplanon, Nuvaring, Veraring (etonogestrel) is a small molecule pharmaceutical. Etonogestrel was first approved as Nuvaring on 2001-10-03.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Nexplanon (discontinued: Implanon)
Combinations
Nuvaring, Veraring (generic drugs available since 2019-12-11)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ethinyl estradiol
+
Etonogestrel
Tradename
Company
Number
Date
Products
NUVARINGOrganonN-021187 RX2001-10-03
1 products, RLD, RS
Etonogestrel
Tradename
Company
Number
Date
Products
NEXPLANONOrganonN-021529 RX2011-05-31
1 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
eluryngANDA2020-12-28
haloetteANDA2022-11-16
nexplanonNew Drug Application2021-07-08
nuvaringNew Drug Application2023-02-06
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Etonogestrel, Implanon, Organon
97575522030-07-28DPU-1
87220372027-09-28DP
108212772027-05-31DP
88887452026-08-28DP
ATC Codes
G: Genito urinary system and sex hormones
G03: Sex hormones and modulators of the genital system
G03A: Hormonal contraceptives for systemic use
G03AC: Progestogen systemic hormonal contraceptives
G03AC08: Etonogestrel
HCPCS
Code
Description
J7295
Ethinyl estradiol and etonogestrel 0.015mg, 0.12mg per 24 hours; monthly vaginal ring, each
J7307
Etonogestrel (contraceptive) implant system, including implant and supplies
Clinical
Clinical Trials
65 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AnesthesiaD000758156
General anesthesiaD000768314
HemodynamicsD00643933
HysteroscopyD015907112
Coronary artery diseaseD003324I25.122
Respiratory insufficiencyD012131HP_0002093J96.9112
DepressionD003863F33.9112
Induced abortionD00002811
DeliriumD003693R41.011
ConfusionD003221F44.8911
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.9112
Critical illnessD016638111
HypertensionD006973EFO_0000537I1011
Drug-related side effects and adverse reactionsD064420T88.711
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Wounds and injuriesD014947T14.844
Postoperative complicationsD01118322
HypotensionD007022EFO_0005251I9522
Drug dose-response relationshipD00430511
Adrenal insufficiencyD00030911
SepsisD018805A41.911
Brain ischemiaD002545I67.8211
Rapid sequence induction and intubationD00007960311
Blood pressureD001794EFO_000432511
Pulmonary hypertensionD006976EFO_0001361I27.2011
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameETONOGESTREL
INNetonogestrel
Description
Etonogestrel is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin and a female contraceptive drug.
Classification
Small molecule
Drug classestrogens; progestins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3C(=C)C[C@@]21CC
Identifiers
PDB
CAS-ID54048-10-1
RxCUI14584
ChEMBL IDCHEMBL1531
ChEBI ID50777
PubChem CID6917715
DrugBankDB00294
UNII ID304GTH6RNH (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
Nexplanon - Organon
$
£
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Nexplanon - Merck Sharp & Dohme
$
£
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Nuvaring - Organon
$
£
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Nuvaring - Merck Sharp & Dohme
$
£
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,188 documents
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Safety
Black-box Warning
Black-box warning for: Eluryng, Haloette, Nuvaring
Adverse Events
Top Adverse Reactions
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716 adverse events reported
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