Skip to content
Ethoxzolamide
Cardrase, Ethamide (ethoxzolamide) is a small molecule pharmaceutical. Ethoxzolamide was first approved as Ethamide on 1982-01-01. The pharmaceutical is active against carbonic anhydrase 14. In addition, it is known to target carbonic anhydrase 1, carbonic anhydrase 7, carbonic anhydrase 12, and carbonic anhydrase 4.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ethoxzolamide
Tradename
Company
Number
Date
Products
ETHAMIDEAllerganN-016144 DISCN1982-01-01
1 products
CARDRASEPharmacia & UpjohnN-011047 DISCN1982-01-01
2 products
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameETHOXZOLAMIDE
INN
Description
Ethoxzolamide is a sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, a diuretic and an antiglaucoma drug. It is a member of benzothiazoles and a sulfonamide.
Classification
Small molecule
Drug classcarbonic anhydrase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOc1ccc2nc(S(N)(=O)=O)sc2c1
Identifiers
PDB5JN9
CAS-ID452-35-7
RxCUI
ChEMBL IDCHEMBL18
ChEBI ID101096
PubChem CID3295
DrugBankDB00311
UNII ID
Target
Agency Approved
CA14
CA14
Organism
Homo sapiens
Gene name
CA14
Gene synonyms
NCBI Gene ID
Protein name
carbonic anhydrase 14
Protein synonyms
CA-XIV, Carbonate dehydratase XIV, Carbonic anhydrase XIV, carbonic dehydratase
Uniprot ID
Mouse ortholog
Car14 (23831)
carbonic anhydrase 14 (Q9WVT6)
Alternate
CA1
CA1
CA7
CA7
CA12
CA12
CA4
CA4
Organism
Homo sapiens
Gene name
CA1
Gene synonyms
NCBI Gene ID
Protein name
carbonic anhydrase 1
Protein synonyms
CA-I, CAB, Carbonate dehydratase I, Carbonic anhydrase B, Carbonic anhydrase I, Cyanamide hydratase CA1, epididymis secretory protein Li 11, epididymis secretory sperm binding protein
Uniprot ID
Mouse ortholog
Car1 (12346)
carbonic anhydrase 1 (Q9DC84)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 450 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
16 adverse events reported
View more details