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Esflurbiprofen
Esflurbiprofen is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target prostaglandin G/H synthase 2.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
M02: Topical products for joint and muscular pain
M02A: Topical products for joint and muscular pain
M02AA: Antiinflammatory preparations, non-steroids for topical use
M02AA29: Esflurbiprofen
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteoarthritisD010003EFO_0002506M15-M1911
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ankle injuriesD016512S93.411
Sprains and strainsD01318011
ContusionsD003288T14.811
Soft tissue injuriesD01769511
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameESFLURBIPROFEN
INNesflurbiprofen
Description
(S)-flurbiprofen is a flurbiprofen. It is an enantiomer of a (R)-flurbiprofen.
Classification
Small molecule
Drug classanti-inflammatory/analgesic agents (ibuprofen type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H](C(=O)O)c1ccc(-c2ccccc2)c(F)c1
Identifiers
PDB
CAS-ID51543-39-6
RxCUI
ChEMBL IDCHEMBL435298
ChEBI ID42446
PubChem CID72099
DrugBank
UNII IDJ5ZZK9P7MX (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PTGS2
PTGS2
Organism
Homo sapiens
Gene name
PTGS2
Gene synonyms
COX2
NCBI Gene ID
Protein name
prostaglandin G/H synthase 2
Protein synonyms
COX-2, cyclooxygenase 2, cyclooxygenase 2b, Cyclooxygenase-2, PGH synthase 2, PGHS-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Uniprot ID
Mouse ortholog
Ptgs2 (19225)
prostaglandin G/H synthase 2 (Q543K3)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 6 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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