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Comtan, Comtess, Entacapone Orion (entacapone) is a small molecule pharmaceutical. Entacapone was first approved as Comtan on 1998-09-16. It is used to treat parkinson disease in the USA. It has been approved in Europe to treat parkinson disease. The pharmaceutical is active against catechol O-methyltransferase. In addition, it is known to target alpha-ketoglutarate-dependent dioxygenase FTO.
Trade Name Comtan, Comtess, Entacapone Orion
Common Name Entacapone
Indication parkinson disease
Drug Class Catechol-O-methyltransferase (COMT) inhibitors
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