Enoblituzumab
Enoblituzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against CD276 antigen.
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Therapeutic Areas
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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HCPCS
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Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Head and neck neoplasms | D006258 | 2 | 2 | 1 | — | — | 4 | ||
| Squamous cell carcinoma of head and neck | D000077195 | — | 2 | 1 | — | — | 2 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | 4 | — | — | — | — | 4 | ||
| Non-small-cell lung carcinoma | D002289 | 3 | — | — | — | — | 3 | ||
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | — | — | — | — | 2 |
| Neuroblastoma | D009447 | EFO_0000621 | 1 | — | — | — | — | 1 | |
| Osteosarcoma | D012516 | 1 | — | — | — | — | 1 | ||
| Ewing sarcoma | D012512 | EFO_0000173 | 1 | — | — | — | — | 1 | |
| Rhabdomyosarcoma | D012208 | 1 | — | — | — | — | 1 | ||
| Desmoplastic small round cell tumor | D058405 | 1 | — | — | — | — | 1 | ||
| Wilms tumor | D009396 | 1 | — | — | — | — | 1 | ||
| Renal cell carcinoma | D002292 | 1 | — | — | — | — | 1 |
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ENOBLITUZUMAB |
| INN | enoblituzumab |
| Description | Enoblituzumab is a monoclonal antibody designed for the treatment of cancer. Formerly known as MGA271, the drug is a humanized IgG1κ monoclonal antibody recognizing human B7-H3, a member of the B7 family of immune regulators.
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| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1353485-38-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545373 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB15017 |
| UNII ID | M6030H73N9 (ChemIDplus, GSRS) |
Target
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Safety
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3 adverse events reported
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