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Inzomelid
Inzomelid is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target NACHT, LRR and PYD domains-containing protein 3.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients11
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameINZOMELID
INNemlenoflast
Description
Inzomelid is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target NACHT, LRR and PYD domains-containing protein 3.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)n1ccc(S(=O)(=O)NC(=O)Nc2c3c(cc4c2CCC4)CCC3)n1
Identifiers
PDB
CAS-ID1995067-59-8
RxCUI
ChEMBL IDCHEMBL4650350
ChEBI ID
PubChem CID
DrugBank
UNII IDSC4RYG0M76 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
NLRP3
NLRP3
Organism
Homo sapiens
Gene name
NLRP3
Gene synonyms
C1orf7, CIAS1, NALP3, PYPAF1
NCBI Gene ID
Protein name
NACHT, LRR and PYD domains-containing protein 3
Protein synonyms
Angiotensin/vasopressin receptor AII/AVP-like, Caterpiller protein 1.1, CLR1.1, cold autoinflammatory syndrome 1 protein, Cold-induced autoinflammatory syndrome 1 protein, Cryopyrin, cryopyrin, NACHT, LRR and PYD domains - containing protein 3, deafness, autosomal dominant 34, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD containing protein 3, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3, PYRIN-containing APAF1-like protein 1
Uniprot ID
Mouse ortholog
Nlrp3 (216799)
NACHT, LRR and PYD domains-containing protein 3 (T1W2H6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 43 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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