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Eltanexor
Eltanexor is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target exportin-1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Myeloid leukemia acuteD015470C92.011———1
Castration-resistant prostatic neoplasmsD06412911———1
Colorectal neoplasmsD01517911———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameELTANEXOR
INNeltanexor
Description
Eltanexor is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target exportin-1.
Classification
Small molecule
Drug classexportin 1 inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
NC(=O)/C(=C/n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)c1cncnc1
Identifiers
PDB—
CAS-ID1642300-52-4
RxCUI—
ChEMBL IDCHEMBL4297623
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDQ59IQJ9NTK (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
XPO1
XPO1
Organism
Homo sapiens
Gene name
XPO1
Gene synonyms
CRM1
NCBI Gene ID
7514
Protein name
exportin-1
Protein synonyms
chromosome region maintenance 1 homolog, Chromosome region maintenance 1 protein homolog, exportin 1 (CRM1 homolog, yeast), exportin-1 (required for chromosome region maintenance)
Uniprot ID
Q99433
Mouse ortholog
Xpo1 (103573)
exportin-1 (Q6P5F9)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 71 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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