Skip to content
Doxycycline anhydrous
Monodox, Oracea, Vibramycin (doxycycline anhydrous) is a small molecule pharmaceutical. Doxycycline anhydrous was first approved as Vibramycin on 1982-01-01. It is used to treat anthrax, bacterial pneumonia, campylobacter infections, cholera, and granuloma inguinale amongst others in the USA.
Download report
Favorite
COVID-19
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
eye diseasesD005128
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Monodox, Oracea, Vibramycin (generic drugs available since 1988-03-09, discontinued: Doxychel)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Doxycycline
Tradename
Company
Number
Date
Products
MONODOXChartwell PharmaceuticalsN-050641 RX1989-12-29
4 products, RLD
ORACEAGaldermaN-050805 RX2006-05-26
1 products, RLD, RS
VIBRAMYCINMylanN-050006 RX1982-01-01
1 products, RLD, RS
Doxycycline calcium
Tradename
Company
Number
Date
Products
VIBRAMYCINMylanN-050480 RX1982-01-01
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
doxycyclineANDA2023-06-13
monodoxNew Drug Application2017-04-26
oracea New Drug Application2017-08-01
vibra-tabs vibramycin calcium vibramycin hyclate vibramycin monohydrateNew Drug Application2021-07-29
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
anthraxD000881A22
bacterial pneumoniaEFO_1001272D018410J15.9
campylobacter infectionsEFO_0007190D002169
choleraD002771A00
granuloma inguinaleEFO_0007291D006100A58
mycoplasma infectionsD009175
plagueEFO_0007481D010930A20
pleural effusionD010996J90
psittacosisEFO_0007410D009956A70
relapsing feverD012061A68
Show 3 more
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Doxycycline, Oracea, Galderma Labs Lp
77495322027-12-19DPU-1063
82067402025-12-24DPU-925
83944052024-04-07DPU-925
83944062024-04-07DPU-925
84703642024-04-07DPU-925
87094782024-04-07U-1063
ATC Codes
A: Alimentary tract and metabolism drugs
A01: Stomatological preparations
A01A: Stomatological preparations
A01AB: Antiinfectives and antiseptics for local oral treatment
A01AB22: Doxycycline
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01A: Tetracycline antibiotics
J01AA: Tetracyclines
J01AA02: Doxycycline
HCPCS
No data
Clinical
Clinical Trials
316 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Acne vulgarisD000152EFO_0003894L703648119
RosaceaD012393L713148117
Covid-19D000086382U07.11353213
InfectionsD007239EFO_00005446410
Periodontal diseasesD010510K05.632239
Chlamydia infectionsD002690EFO_0007205A74.91258
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.92316
SyphilisD013587EFO_0007504A53.9246
Lyme diseaseD008193A69.22215
Erythema chronicum migransD015787A26.0145
Show 51 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AmyloidosisD000686EFO_1001875E8513114
Chronic periodontitisD055113EFO_0006343K05.3324
Graves ophthalmopathyD049970EFO_100146613114
Filarial elephantiasisD004605EFO_0007272B74.033
LymphedemaD008209Q82.033
FilariasisD005368B7433
TuberculosisD014376EFO_0000774A15-A19213
Heart failureD006333EFO_0003144I50112
Ventricular remodelingD020257112
St elevation myocardial infarctionD000072657112
Show 22 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179213
Ulcerative colitisD003093EFO_0000729K51213
Pelvic inflammatory diseaseD000292EFO_1001388N70-N77112
Non-small-cell lung carcinomaD002289112
AnthraxD000881A22112
Pancreatic neoplasmsD010190EFO_0003860C25112
Breast neoplasmsD001943EFO_0003869C50112
T-cell lymphoma cutaneousD016410C84.A112
Atopic dermatitisD003876EFO_0000274L2022
MansonelliasisD008368EFO_0007357B74.422
Show 57 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients628
Therapeutic equivalencyD01381055
Tennis elbowD013716EFO_1001896M77.1112
Arteriovenous malformationsD00116522
Elbow tendinopathyD000070639M77.011
Coronavirus infectionsD018352EFO_0007224B34.211
Severe acute respiratory syndrome-related coronavirusD045473NCBITaxon_22785911
Cardio-renal syndromeD05934711
Intracranial aneurysmD002532EFO_0003870I67.111
Cavernous hemangiomaD006392D18.011
Show 6 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Tick-borne encephalitisD004675EFO_1001309A8422
Rheumatoid arthritisD001172EFO_0000685M06.922
MalariaD008288EFO_0001068B5411
Mycoplasma pneumoniaD011019EFO_0007387J15.711
Aseptic meningitisD008582EFO_1000823G03.011
Staphylococcus aureusD013211NCBITaxon_128011
Female infertilityD007247EFO_0008560N9711
Liver cirrhosisD008103EFO_0001422K74.011
InfertilityD007246EFO_000054511
Diet therapyD00403511
Show 23 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameDOXYCYCLINE ANHYDROUS
INNdoxycycline
Description
Doxycycline is tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. It has a role as an antibacterial drug, an antimalarial, a geroprotector, an anti-inflammatory agent and an immunomodulator.
Classification
Small molecule
Drug classantibiotics (tetracycline derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H]1c2cccc(O)c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@@H]21
Identifiers
PDB
CAS-ID564-25-0
RxCUI1545992
ChEMBL IDCHEMBL1433
ChEBI ID50845
PubChem CID54671203
DrugBankDB00254
UNII ID334895S862 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
Doxycycline - Fortress Biotech, Inc.
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Doxycycline - Journey Medical
$
£
Mock data
Subscribe for the real data
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 72,122 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
16,260 adverse events reported
View more details