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Docosanol
Abreva (docosanol) is a small molecule pharmaceutical. Docosanol was first approved as Abreva on 2000-07-25. It is used to treat blister in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Abreva (generic drugs available since 2018-11-19)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Docosanol
Tradename
Company
Number
Date
Products
ABREVAGSKN-020941 OTC2000-07-25
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
abrevaOTC monograph final2023-05-19
cold sore fever blister treatmentANDA2023-06-06
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
blisterD001768
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
D06: Antibiotics and chemotherapeutics for dermatological use
D06B: Chemotherapeutics for topical use
D06BB: Antivirals, topical
D06BB11: Docosanol
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atrial fibrillationD001281EFO_0000275I48.0112
Cardiovascular diseasesD002318EFO_0000319I9811
Heart diseasesD006331EFO_0003777I51.911
Cardiac arrhythmiasD001145EFO_0004269I49.911
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDOCOSANOL
INN
Description
Docosan-1-ol is a long-chain primary fatty alcohol that is docosane substituted by a hydroxy group at position 1. It has a role as an antiviral agent. It is a long-chain primary fatty alcohol and a fatty alcohol 22:0. It derives from a hydride of a docosane.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCCCCCCCCCCCCCCCCCCCCO
Identifiers
PDB
CAS-ID661-19-8
RxCUI594680
ChEMBL IDCHEMBL1200453
ChEBI ID31000
PubChem CID12620
DrugBankDB00632
UNII ID
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 356 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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786 adverse events reported
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