Skip to content
Dinaciclib
Dinaciclib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cyclin-dependent kinase 2, cyclin-dependent kinase 9, cyclin-dependent kinase 5, and cyclin-dependent kinase 1.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
18 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
B-cell chronic lymphocytic leukemiaD015451C91.1321——5
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101C90.031———4
Breast neoplasmsD001943EFO_0003869C5021———3
Myeloid leukemia acuteD015470C92.011———2
MelanomaD00854512———2
Mantle-cell lymphomaD020522C83.1—1———1
Non-small-cell lung carcinomaD002289—1———1
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.0—1———1
Prolymphocytic leukemiaD01546311———1
LentigoD007911L81.4—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C802————2
Non-hodgkin lymphomaD008228C85.92————2
Triple negative breast neoplasmsD0647262————2
Male breast neoplasmsD0185671————1
Pancreatic neoplasmsD010190EFO_0003860C251————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameDINACICLIB
INNdinaciclib
Description
2-[(2S)-1-[3-ethyl-7-[(1-oxido-3-pyridin-1-iumyl)methylamino]-5-pyrazolo[1,5-a]pyrimidinyl]-2-piperidinyl]ethanol is a pyrazolopyrimidine.
Classification
Small molecule
Drug classcyclin dependent kinase inhibitors (formerly-cidib)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@H]3CCO)nc12
Identifiers
PDB—
CAS-ID779353-01-4
RxCUI—
ChEMBL IDCHEMBL2103840
ChEBI ID—
PubChem CID46926350
DrugBankDB12021
UNII ID4V8ECV0NBQ (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CDK2
CDK2
CDK9
CDK9
CDK5
CDK5
CDK1
CDK1
Organism
Homo sapiens
Gene name
CDK2
Gene synonyms
CDKN2
NCBI Gene ID
1017
Protein name
cyclin-dependent kinase 2
Protein synonyms
cdc2-related protein kinase, Cell division protein kinase 2, p33 protein kinase
Uniprot ID
P24941
Mouse ortholog
Cdk2 (12566)
cyclin-dependent kinase 2 (P97377)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 1,428 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
18 adverse events reported
View more details