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Diethylpropion
Tenuate, Tepanil (diethylpropion) is a small molecule pharmaceutical. Diethylpropion was first approved as Tepanil on 1982-01-01. It is used to treat obesity in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nutritional and metabolic diseasesD009750
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Diethylpropion hydrochloride
Tradename
Company
Number
Date
Products
TEPANIL3MN-011673 DISCN1982-01-01
1 products
TEPANIL TEN-TAB3MN-017956 DISCN1982-01-01
1 products
TENUATENostrum LaboratoriesN-011722 DISCN1982-01-01
1 products, RLD
TENUATE DOSPANNostrum LaboratoriesN-012546 DISCN1982-01-01
1 products, RLD
TENUATESanofiN-017668 DISCN1982-01-01
1 products
TENUATESanofiN-017669 DISCN1982-01-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
diethylpropion hydrochlorideANDA2023-06-19
tepanil2006-07-26
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
obesityEFO_0001073D009765E66.9
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A08: Antiobesity preparations, excl. diet products
— A08A: Antiobesity preparations, excl. diet products
— A08AA: Centrally acting antiobesity products
— A08AA03: Amfepramone
HCPCS
No data
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LoiasisD008118B74.3—1—1—2
InfectionsD007239EFO_0000544———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Filarial elephantiasisD004605EFO_0007272B74.0—32—38
YawsD015001EFO_0007548A66—11——2
TrachomaD014141A71——1——1
ScabiesD012532B86——1——1
StrongyloidiasisD013322EFO_0007501B78——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Wounds and injuriesD014947T14.8—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Parasitic diseasesD010272EFO_0001067B88————11
OnchocerciasisD009855EFO_0007402B73————11
FilariasisD005368B74————11
MansonelliasisD008368EFO_0007357B74.4————11
HelminthiasisD006373EFO_1001342B65-B83————11
Hiv infectionsD015658EFO_0000764B20————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDIETHYLPROPION
INNamfepramone
Description
Diethylpropion is an aromatic ketone that is propiophenone in which one of the hydrogens alpha- to the carbonyl is substituted by a diethylamino group. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as the hydrochloride as an anoretic in the short term management of obesity. It has a role as an appetite depressant. It is a tertiary amine and an aromatic ketone. It is functionally related to a propiophenone.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCN(CC)C(C)C(=O)c1ccccc1
Identifiers
PDB—
CAS-ID90-84-6
RxCUI—
ChEMBL IDCHEMBL1194666
ChEBI ID4530
PubChem CID7029
DrugBankDB00937
UNII IDQ94YYU22B8 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 644 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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100 adverse events reported
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