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Demeclocycline
Declomycin (demeclocycline) is a small molecule pharmaceutical. Demeclocycline was first approved as Declomycin on 1982-01-01. It is used to treat acne vulgaris, actinomycosis, bacterial infections, campylobacter infections, and cholera amongst others in the USA.
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Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
nervous system diseasesD009422
eye diseasesD005128
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
nutritional and metabolic diseasesD009750
endocrine system diseasesD004700
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Demeclocycline hydrochloride
Tradename
Company
Number
Date
Products
DECLOMYCINCorePharmaN-050261 DISCN1982-01-01
3 products
DECLOMYCINLederle LaboratoriesN-050257 DISCN1982-01-01
1 products
DECLOMYCINLederle LaboratoriesN-050262 DISCN1982-01-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
demeclocycline hydrochlorideANDA2023-02-28
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
acne vulgarisEFO_0003894D000152L70
actinomycosisEFO_0007128D000196A42
bacterial infections—D001424A49
campylobacter infectionsEFO_0007190D002169—
cholera—D002771A00
clostridium infectionsEFO_1000874D003015A05.2
gonorrheaDOID_7551D006069A54
inappropriate adh syndromeEFO_1000982D007177E22.2
lymphogranuloma venereumEFO_0007353D008219A55
mycoplasma pneumoniaEFO_0007387D011019J15.7
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06A: Antibiotics for topical use
— D06AA: Tetracycline and derivatives, topical antibiotics
— D06AA01: Demeclocycline
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01A: Tetracycline antibiotics
— J01AA: Tetracyclines
— J01AA01: Demeclocycline
HCPCS
No data
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDEMECLOCYCLINE
INNdemeclocycline
Description
Demeclocycline (INN, BAN, USAN, brand name Declomycin) is a tetracycline antibiotic which was derived from a mutant strain of Streptomyces aureofaciens.
Classification
Small molecule
Drug classantibiotics (tetracycline derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)ccc(Cl)c4[C@@H](O)[C@H]3C[C@@H]12
Identifiers
PDB—
CAS-ID127-33-3
RxCUI3154
ChEMBL IDCHEMBL1591
ChEBI ID4392
PubChem CID5311063
DrugBankDB00618
UNII ID5R5W9ICI6O (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 1,110 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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