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Cytisinicline
Cytisinicline is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N07: Other nervous system drugs in atc
N07B: Drugs used in addictive disorders
N07BA: Drugs used in nicotine dependence
N07BA04: Cytisinicline
HCPCS
No data
Clinical
Clinical Trials
20 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Smoking cessationD016540EFO_00043196461116
Tobacco use disorderD014029F17112
AlcoholismD000437EFO_0003829F10.111
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B20111
SmokingD012907EFO_0003768F17111
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175C34.9011
Diet therapyD00403511
InflammationD00724911
ExerciseD015444EFO_000048311
VapingD00007213711
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Renal insufficiencyD051437HP_0000083N1911
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Coronary artery diseaseD003324I25.111
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCYTISINICLINE
INNcytisinicline
Description
Cytisine is an organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking. It has a role as a nicotinic acetylcholine receptor agonist, a phytotoxin and a plant metabolite. It is an alkaloid, an organic heterotricyclic compound, a secondary amino compound, a lactam and a bridged compound.
Classification
Small molecule
Drug classnicotinic acetylcholine receptor partial agonists/agonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=c1cccc2n1C[C@@H]1CNC[C@H]2C1
Identifiers
PDB
CAS-ID485-35-8
RxCUI1723152
ChEMBL IDCHEMBL497939
ChEBI ID4055
PubChem CID10235
DrugBankDB09028
UNII ID53S5U404NU (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 7 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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