Concizumab
Concizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target tissue factor pathway inhibitor.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemophilia a | D006467 | EFO_0007267 | D66 | 2 | 3 | 3 | — | 1 | 9 |
| Hemophilia b | D002836 | D67 | 1 | 1 | 2 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemostasis | D006487 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CONCIZUMAB |
| INN | concizumab |
| Description | Concizumab, sold under the brand name Alhemo, is a monoclonal antibody used for the treatment of hemophilia B. It is an anti-tissue factor pathway inhibitor.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297730 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB12820 |
| UNII ID | 68603V9EAF (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
TFPI
TFPI
Organism
Homo sapiens
Gene name
TFPI
Gene synonyms
LACI, TFPI1
NCBI Gene ID
Protein name
tissue factor pathway inhibitor
Protein synonyms
anti-convertin, EPI, Extrinsic pathway inhibitor, LACI, Lipoprotein-associated coagulation inhibitor, tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Uniprot ID
Mouse ortholog
Tfpi (21788)
tissue factor pathway inhibitor (Q9Z2U8)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 172 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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