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Citicoline
Citicoline is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N06: Psychoanaleptics
N06B: Psychostimulants, agents used for adhd and nootropics
N06BX: Other psychostimulants and nootropics in atc
N06BX06: Citicoline
HCPCS
No data
Clinical
Clinical Trials
45 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
GlaucomaD005901EFO_0000516H40134
Bipolar disorderD001714EFO_0000289F30.9213
Cerebral infarctionD002544I63112
Cocaine-related disordersD019970F14112
Ischemic optic neuropathyD018917EFO_1000809H47.0122
AlcoholismD000437EFO_0003829F10.122
DeliriumD003693R41.011
Neural conductionD00943111
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Traumatic brain injuriesD000070642S061113
Ischemic strokeD000083242112
StrokeD020521EFO_0000712I63.922
Open-angle glaucomaD005902EFO_0004190H40.1112
ManiaD000087122F3011
HypoxiaD000860R09.0211
Brain hypoxia-ischemiaD020925EFO_1000846P91.611
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SchizophreniaD012559EFO_0000692F2022
Substance-related disordersD019966EFO_0003890F13112
Brain injuriesD001930S06.911
Marijuana abuseD002189EFO_0007191F1211
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients44
Amphetamine-related disordersD019969EFO_0004701F1511
Major depressive disorderD003865EFO_0003761F2211
Neurodegenerative diseasesD019636EFO_0005772G31.911
Uveal neoplasmsD014604EFO_100123011
Alzheimer diseaseD000544EFO_0000249F0311
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCITICOLINE
INNciticoline
Description
CDP-choline is a member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes. It has a role as a human metabolite, a psychotropic drug, a neuroprotective agent, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a member of phosphocholines and a member of nucleotide-(amino alcohol)s. It is functionally related to a CDP. It is a conjugate base of a CDP-choline(1+).
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[N+](C)(C)CCOP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O
Identifiers
PDB
CAS-ID987-78-0
RxCUI997602
ChEMBL IDCHEMBL1618340
ChEBI ID49086
PubChem CID13804
DrugBankDB12153
UNII ID536BQ2JVC7 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 1,456 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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113 adverse events reported
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