Cisplatin
Platinol, Platinol-aq (cisplatin) is a small molecule pharmaceutical. Cisplatin was first approved as Cisplatin on 1982-01-01. It is used to treat amelanotic melanoma, astrocytoma, breast neoplasms, cystic mesothelioma, and esophageal neoplasms amongst others in the USA.
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Therapeutic Areas
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cisplatin
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CISPLATIN | HQ Specialty Pharma | N-018057 RX | 1982-01-01 | 2 products, RLD, RS |
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cisplatin | unapproved drug for use in drug shortage | 2023-06-02 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| amelanotic melanoma | — | D018328 | — |
| astrocytoma | EFO_0000271 | D001254 | — |
| breast neoplasms | EFO_0003869 | D001943 | C50 |
| cystic mesothelioma | — | D018261 | — |
| esophageal neoplasms | — | D004938 | C15 |
| hodgkin disease | — | D006689 | C81 |
| lung neoplasms | — | D008175 | C34.90 |
| multiple myeloma | — | D009101 | C90.0 |
| neuroblastoma | EFO_0000621 | D009447 | — |
| non-hodgkin lymphoma | — | D008228 | C85.9 |
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Agency Specific
FDA
EMA
No data
Patent Expiration
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HCPCS
Code | Description |
|---|---|
| J9060 | Injection, cisplatin, powder or solution, 10 mg |
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 5 | 1 | 5 | — | — | 11 |
| Cognitive dysfunction | D060825 | G31.84 | 1 | 1 | 1 | — | — | 3 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 2 | — | — | — | — | 2 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CISPLATIN |
| INN | cisplatin |
| Description | Cisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein.
|
| Classification | Small molecule |
| Drug class | antineoplastics (platinum derivatives) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cl[Pt]Cl.N.N |
Identifiers
| PDB | — |
| CAS-ID | 15663-27-1 |
| RxCUI | 2555 |
| ChEMBL ID | CHEMBL11359 |
| ChEBI ID | — |
| PubChem CID | 5702198 |
| DrugBank | DB00515 |
| UNII ID | Q20Q21Q62J (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 190,250 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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45 adverse events reported
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