Chlorphentermine
Pre-sate (chlorphentermine) is a small molecule pharmaceutical. Chlorphentermine was first approved as Pre-sate on 1982-01-01.
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Chlorphentermine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PRE-SATE | Pfizer | N-014696 DISCN | 1982-01-01 | 1 products |
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681 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 12 | 12 | 25 | 27 | 14 | 89 |
| Postoperative pain | D010149 | G89.18 | 4 | 8 | 13 | 22 | 12 | 58 | |
| Healthy volunteers/patients | — | 50 | — | — | 4 | 2 | 56 | ||
| Patent ductus arteriosus | D004374 | HP_0001643 | Q25.0 | 2 | 9 | 10 | 9 | 12 | 39 |
| Fever | D005334 | HP_0001945 | R50.9 | 2 | — | 5 | 10 | 3 | 20 |
| Low back pain | D017116 | HP_0003419 | M54.5 | — | 2 | 4 | 10 | 2 | 17 |
| Acute pain | D059787 | R52 | 2 | 2 | 5 | 7 | 1 | 17 | |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 3 | 3 | 6 | 2 | — | 14 |
| Analgesia | D000698 | — | 2 | 6 | 6 | — | 13 | ||
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 3 | 2 | — | 3 | 3 | 10 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | C80 | — | 2 | 1 | — | 1 | 4 | |
| Cough | D003371 | HP_0012735 | R05 | 1 | — | 2 | — | 1 | 4 |
| Local anesthesia | D000772 | — | 2 | 1 | — | 1 | 3 | ||
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | 1 | — | 1 | 3 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | 1 | — | 1 | 3 |
| Altitude sickness | D000532 | EFO_1000782 | T70.29 | 1 | — | 1 | — | 1 | 3 |
| Impacted tooth | D014095 | HP_0011079 | K01.1 | — | 1 | 2 | — | 1 | 3 |
| Sprains and strains | D013180 | — | — | 3 | — | — | 3 | ||
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | 1 | 1 | — | — | 2 |
| Cachexia | D002100 | HP_0004326 | R64 | — | — | 1 | — | 1 | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 2 | — | — | — | 2 |
| Phimosis | D010688 | EFO_1001104 | N47.1 | 1 | 1 | — | — | — | 2 |
| Paraphimosis | D010263 | EFO_1001086 | N47.2 | 1 | 1 | — | — | — | 2 |
| Balanitis | D001446 | EFO_1000833 | N48.1 | 1 | 1 | — | — | — | 2 |
| Retinopathy of prematurity | D012178 | EFO_1001158 | H35.1 | — | 1 | — | — | 1 | 2 |
| Malaria | D008288 | EFO_0001068 | B54 | 1 | 2 | — | — | — | 2 |
| Abdominal hernia | D046449 | K46 | — | 1 | — | — | 1 | 2 | |
| Bronchopulmonary dysplasia | D001997 | P27.8 | — | 2 | — | — | — | 2 | |
| Soft tissue injuries | D017695 | — | 1 | — | — | 1 | 2 | ||
| Allergic rhinitis | D065631 | J30.9 | 1 | 1 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | 5 | — | — | — | — | 5 | ||
| Pharmacokinetics | D010599 | 1 | — | — | — | 1 | 2 | ||
| Drug interactions | D004347 | 1 | — | — | — | — | 1 | ||
| Pure autonomic failure | D054970 | 1 | — | — | — | — | 1 | ||
| Orthostatic hypotension | D007024 | I95.1 | 1 | — | — | — | — | 1 | |
| Hematologic neoplasms | D019337 | 1 | — | — | — | — | 1 | ||
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | C91.0 | 1 | — | — | — | — | 1 | |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | 1 | — | — | — | — | 1 | |
| Hodgkin disease | D006689 | C81 | 1 | — | — | — | — | 1 | |
| Systemic mastocytosis | D034721 | C96.21 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | — | 3 | 3 |
| Leg ulcer | D007871 | — | — | — | — | 2 | 2 | ||
| Colonic neoplasms | D003110 | C18 | — | — | — | — | 1 | 1 | |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | — | 1 | 1 |
| Urinary calculi | D014545 | N20.9 | — | — | — | — | 1 | 1 | |
| Pediatric obesity | D063766 | — | — | — | — | 1 | 1 | ||
| Appetitive behavior | D001070 | — | — | — | — | 1 | 1 | ||
| Platelet aggregation | D010974 | GO_0070527 | — | — | — | — | 1 | 1 | |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 1 | 1 |
| Forearm injuries | D005543 | S59.91 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CHLORPHENTERMINE |
| INN | chlorphentermine |
| Description | Chlorphentermine is a member of amphetamines. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(N)Cc1ccc(Cl)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 461-78-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201269 |
| ChEBI ID | 3646 |
| PubChem CID | 10007 |
| DrugBank | DB01556 |
| UNII ID | NHW07912O7 (ChemIDplus, GSRS) |
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Additional graphs summarizing 225 documents
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Safety
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36,488 adverse events reported
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