Chlormadinone acetate
Chlormadinone acetate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Therapeutic Areas
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03A: Hormonal contraceptives for systemic use
— G03AA: Progestogens and estrogen systemic contraceptives, fixed combinations
— G03AA15: Chlormadinone and ethinylestradiol
— G03AB: Progestogens and estrogens systemic contraceptives, sequential preparations
— G03AB07: Chlormadinone and ethinylestradiol
— G03D: Progestogen sex hormones and modulators of the genital system
— G03DB: Pregnadien derivatives, progestogens
— G03DB06: Chlormadinone
— G03F: Progestogens and estrogens in combination
— G03FB: Progestogens and estrogens, sequential preparations
— G03FB03: Chlormadinone and estrogen
HCPCS
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Clinical
Clinical Trials
112 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Contraception | D003267 | 5 | 3 | — | 8 | 7 | 21 | ||
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 8 | 2 | 1 | — | 10 | |
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 3 | — | 1 | 3 | 8 |
| Postmenopause | D017698 | 1 | 1 | 3 | 1 | — | 6 | ||
| Endometrial hyperplasia | D004714 | N85.0 | — | 2 | 1 | 2 | — | 5 | |
| Hot flashes | D019584 | — | 2 | 2 | 1 | — | 5 | ||
| Hiv | D006678 | O98.7 | — | 1 | — | 3 | 1 | 5 | |
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | — | — | 3 | 1 | — | 4 |
| Metrorrhagia | D008796 | HP_0100608 | N92.1 | — | — | 1 | 2 | 1 | 4 |
| Infertility | D007246 | EFO_0000545 | — | — | 1 | 2 | — | 3 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | 1 | 4 | — | 1 | 5 |
| Coronary disease | D003327 | — | 1 | 5 | — | — | 5 | ||
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | 5 | — | — | 5 |
| Menopause | D008593 | EFO_0003922 | N95 | — | 1 | 2 | — | — | 3 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | 2 | — | — | 3 |
| Healthy volunteers/patients | — | 2 | 1 | 1 | — | — | 3 | ||
| Menorrhagia | D008595 | N92.0 | — | — | 2 | — | 1 | 3 | |
| Uterine hemorrhage | D014592 | — | — | 1 | — | 2 | 3 | ||
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 3 | — | — | 3 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | 1 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Endometrioid carcinoma | D018269 | — | 2 | — | — | — | 2 | ||
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 1 | — | — | — | 1 |
| Prehypertension | D058246 | — | 1 | — | — | — | 1 | ||
| Primary ovarian insufficiency | D016649 | EFO_0004266 | E28.3 | — | 1 | — | — | — | 1 |
| Persistent fetal circulation syndrome | D010547 | EFO_1001103 | P29.3 | — | 1 | — | — | — | 1 |
| Myelodysplastic syndromes | D009190 | D46 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postcoital contraception | D044363 | 1 | — | — | — | 1 | 2 | ||
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | — | 1 | 1 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | — | 1 | 1 |
| Cognitive dysfunction | D060825 | G31.84 | — | — | — | — | 1 | 1 | |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | — | — | — | 1 | 1 |
| Contraception behavior | D003268 | — | — | — | — | 1 | 1 | ||
| Hormonal contraception | D000080282 | — | — | — | — | 1 | 1 | ||
| Breast feeding | D001942 | — | — | — | — | 1 | 1 | ||
| Chlamydia infections | D002690 | EFO_0007205 | A74.9 | — | — | — | — | 1 | 1 |
| Neisseriaceae infections | D016870 | EFO_1001377 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CHLORMADINONE ACETATE |
| INN | chlormadinone |
| Description | Chlormadinone acetate is a corticosteroid hormone. |
| Classification | Small molecule |
| Drug class | Progestogen; Progestin; Progestogen ester; Antigonadotropin; Steroidal antiandrogen |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C |
Identifiers
| PDB | — |
| CAS-ID | 302-22-7 |
| RxCUI | 2369 |
| ChEMBL ID | CHEMBL110691 |
| ChEBI ID | 31394 |
| PubChem CID | 9324 |
| DrugBank | DB15903 |
| UNII ID | SDS4N642GG (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
0 adverse events reported
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