Chloramphenicol
Chlorofair, Chloromycetin, Chloromyxin, Chloroptic, Chloroptic-p, Econochlor, Mychel-s, Ophthochlor, Ophthocort, Optomycin (chloramphenicol) is a small molecule pharmaceutical. Chloramphenicol was first approved as Chloroptic on 1982-01-01. It is used to treat bacterial eye infections, bacterial infections, bacteroides infections, haemophilus infections, and meningococcal meningitis amongst others in the USA. It is known to target HTH-type transcriptional regulator TtgR.
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Commercial
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Chloramphenicol
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CHLOROPTIC | Allergan | N-050091 DISCN | 1982-01-01 | 1 products |
| CHLOROMYCETIN | Pfizer | N-050153 DISCN | 1982-01-01 | 1 products |
| CHLOROMYCETIN | Pfizer | N-050183 DISCN | 1982-01-01 | 1 products |
| CHLOROMYCETIN | Parkedale Pharmaceuticals | N-050143 DISCN | 1982-01-01 | 1 products |
| CHLOROMYCETIN | Parkedale Pharmaceuticals | N-050156 DISCN | 1982-01-01 | 1 products |
| CHLOROMYCETIN | Parkedale Pharmaceuticals | N-050205 DISCN | 1982-01-01 | 1 products |
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Chloramphenicol
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Hydrocortisone acetate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CHLOROMYCETIN HYDROCORTISONE | Parkedale Pharmaceuticals | N-050202 DISCN | 1982-01-01 | 1 products |
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Chloramphenicol
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Hydrocortisone acetate
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Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| OPHTHOCORT | Parkedale Pharmaceuticals | N-050201 DISCN | 1982-01-01 | 1 products |
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Chloramphenicol
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Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CHLOROMYXIN | Pfizer | N-050203 DISCN | 1982-01-01 | 1 products |
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Chloramphenicol sodium succinate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CHLOROMYCETIN | Parkedale Pharmaceuticals | N-050155 DISCN | 1982-01-01 | 1 products, RLD |
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| bacterial eye infections | — | D015818 | — |
| bacterial infections | — | D001424 | A49 |
| bacteroides infections | EFO_1000832 | D001442 | — |
| haemophilus infections | EFO_1001127 | D006192 | — |
| meningococcal meningitis | EFO_1001040 | D008585 | A39.0 |
| otitis externa | EFO_0009560 | D010032 | H60 |
| rickettsia infections | EFO_1001162 | D012282 | A75-A79 |
| salmonella infections | EFO_1001418 | D012480 | A02.9 |
| streptococcal infections | EFO_1001476 | D013290 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06A: Antibiotics for topical use
— D06AX: Other antibiotics for topical use in atc
— D06AX02: Chloramphenicol
— D10: Anti-acne preparations
— D10A: Anti-acne preparations for topical use
— D10AF: Antiinfectives for treatment of acne
— D10AF03: Chloramphenicol
G: Genito urinary system and sex hormones
— G01: Gynecological antiinfectives and antiseptics
— G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
— G01AA: Antibiotics, gynecological
— G01AA05: Chloramphenicol
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01B: Amphenicols
— J01BA: Amphenicol antibacterials, systemic
— J01BA01: Chloramphenicol
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA01: Chloramphenicol
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA01: Chloramphenicol
— S03: Ophthalmological and otological preparations
— S03A: Antiinfectives, ophthalmologic and otologic
— S03AA: Antiinfectives
— S03AA08: Chloramphenicol
HCPCS
Code | Description |
|---|---|
| J0720 | Injection, chloramphenicol sodium succinate, up to 1 gm |
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CHLORAMPHENICOL |
| INN | chloramphenicol |
| Description | Chloramphenicol is an organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. It has a role as an antimicrobial agent, an antibacterial drug, a protein synthesis inhibitor, an Escherichia coli metabolite, a Mycoplasma genitalium metabolite and a geroprotector. It is an organochlorine compound, a diol, a C-nitro compound and a carboxamide. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C(N[C@H](CO)[C@H](O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl |
Target
Agency Approved
No data
Alternate
ttgR
ttgR
Organism
Pseudomonas putida (strain DOT-T1E)
Gene name
ttgR
Gene synonyms
NCBI Gene ID
—
Protein name
HTH-type transcriptional regulator TtgR
Protein synonyms
Toluene efflux pump ttgABC operon repressor
Uniprot ID
Mouse ortholog
—
—
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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