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Cefuroxime
Zinacef (cefuroxime) is a small molecule pharmaceutical. Cefuroxime was first approved as Zinacef on 1983-10-19. It is used to treat bacterial infections, bacterial meningitis, bacterial pneumonia, escherichia coli infections, and gonorrhea amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
stomatognathic diseasesD009057
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
nervous system diseasesD009422
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Zinacef (generic drugs available since 1997-05-30, discontinued: Kefurox)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cefuroxime sodium
Tradename
Company
Number
Date
Products
CEFUROXIME AND DEXTROSE IN DUPLEX CONTAINERB. Braun MedicalN-050780 RX2001-02-21
2 products, RLD, RS
ZINACEFPAI PharmaN-050558 RX1983-10-19
3 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
cefuroxime axetilANDA2023-06-07
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
bacterial meningitisEFO_1000831D016920G00
bacterial pneumoniaEFO_1001272D018410J15.9
escherichia coli infectionsEFO_1001318D004927B96.20
gonorrheaDOID_7551D006069A54
haemophilus infectionsEFO_1001127D006192—
impetigoEFO_1000714D007169L01
infectious bone diseases—D001850—
klebsiella infectionsEFO_1001353D007710—
lyme disease—D008193A69.2
Show 6 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DC: Second-generation cephalosporins
— J01DC02: Cefuroxime
— J01R: Combinations of antibacterials
— J01RA: Combinations of antibacterials
— J01RA03: Cefuroxime and metronidazole
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA27: Cefuroxime
HCPCS
Code
Description
J0697
Injection, sterile cefuroxime sodium, per 750 mg
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial meningitisD016920EFO_1000831G00————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCEFUROXIME
INNcefuroxime
Description
Cefuroxime is a 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain. It has a role as a drug allergen. It is a 3-(carbamoyloxymethyl)cephalosporin, a member of furans and an oxime O-ether.
Classification
Small molecule
Drug classcephalosporins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@H]12)c1ccco1
Identifiers
PDB—
CAS-ID55268-75-2
RxCUI2194
ChEMBL IDCHEMBL1436
ChEBI ID3515
PubChem CID5479529
DrugBankDB01112
UNII IDO1R9FJ93ED (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 16,141 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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52 adverse events reported
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