Cefpiramide
Cefpiramide is a small molecule pharmaceutical. Cefpiramide was first approved as Cefpiramide sodium on 1989-01-31.
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Abbreviated New Drug Application (ANDA)
Cefpiramide sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CEFPIRAMIDE SODIUM | Wyeth | N-050633 DISCN | 1989-01-31 | 3 products |
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16 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung diseases | D008171 | EFO_0003818 | J98.4 | — | 1 | 1 | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | — | 1 | — | — | 1 |
| Pancreatic diseases | D010182 | K86.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Appendicitis | D001064 | EFO_0007149 | K37 | — | 1 | — | — | 1 | 2 |
| Wound infection | D014946 | — | 1 | — | — | — | 1 | ||
| Endometritis | D004716 | EFO_1001312 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infectious pregnancy complications | D011251 | — | — | — | — | 1 | 1 | ||
| Antibiotic prophylaxis | D019072 | — | — | — | — | 1 | 1 | ||
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | |
| Bile duct neoplasms | D001650 | — | — | — | — | 1 | 1 | ||
| Klatskin tumor | D018285 | EFO_1001005 | — | — | — | — | 1 | 1 | |
| Choledocholithiasis | D042883 | EFO_1000865 | — | — | — | — | 1 | 1 | |
| Congenital heart defects | D006330 | HP_0001627 | Q24.9 | — | — | — | — | 1 | 1 |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | — | — | — | 1 | 1 |
| Sepsis | D018805 | A41.9 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CEFPIRAMIDE |
| INN | cefpiramide |
| Description | Cefpiramide is a third-generation cephalosporin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and (R)-2-{[(4-hydroxy-6-methylpyridin-3-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It has a broad spectrum of antibacterial activity. It has a role as an antibacterial drug. It is a cephalosporin and a carboxylic acid. It is a conjugate acid of a cefpiramide(1-). |
| Classification | Small molecule |
| Drug class | cephalosporins |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cc(O)c(C(=O)N[C@@H](C(=O)N[C@@H]2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CS[C@H]23)c2ccc(O)cc2)cn1 |
Identifiers
| PDB | — |
| CAS-ID | 70797-11-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201204 |
| ChEBI ID | 59213 |
| PubChem CID | 636405 |
| DrugBank | DB00430 |
| UNII ID | P936YA152N (ChemIDplus, GSRS) |
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Safety
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574 adverse events reported
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