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Carboplatin
Paraplatin (carboplatin) is a small molecule pharmaceutical. Carboplatin was first approved as Paraplatin on 1989-03-03. It is used to treat bone marrow diseases, breast neoplasms, central nervous system neoplasms, endometrial neoplasms, and esophageal neoplasms amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
digestive system diseasesD004066
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
hemic and lymphatic diseasesD006425
skin and connective tissue diseasesD017437
endocrine system diseasesD004700
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Carboplatin
Tradename
Company
Number
Date
Products
PARAPLATINCordenPharmaN-019880 DISCN1989-03-03
3 products, RLD
PARAPLATINCordenPharmaN-020452 DISCN2003-07-14
4 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
carboplatinANDA2022-12-02
paraplatinANDA2020-08-24
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bone marrow diseases—D001855—
breast neoplasmsEFO_0003869D001943C50
central nervous system neoplasms—D016543—
endometrial neoplasmsEFO_0004230D016889—
esophageal neoplasms—D004938C15
germ cell and embryonal neoplasms—D009373—
lung neoplasms—D008175C34.90
osteosarcoma—D012516—
ovarian neoplasmsEFO_0003893D010051C56
urinary bladder neoplasms—D001749C67
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
L: Antineoplastic and immunomodulating agents
— L01: Antineoplastic agents
— L01X: Other antineoplastic agents in atc
— L01XA: Platinum compounds, antineoplastic drugs
— L01XA02: Carboplatin
HCPCS
Code
Description
J9045
Injection, carboplatin, 50 mg
Clinical
Clinical Trials
2567 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289136334174816614
Ovarian neoplasmsD010051EFO_0003893C561001626429293
Lung neoplasmsD008175C34.90461685818257
Breast neoplasmsD001943EFO_0003869C50531664257247
NeoplasmsD009369C80159571125206
Squamous cell carcinoma of head and neckD000077195175491175
Squamous cell neoplasmsD01830791881235
Large b-cell lymphoma diffuseD016403C83.3161821131
Adenocarcinoma of lungD00007719251661227
AdenocarcinomaD00023091451—24
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Fallopian tube neoplasmsD005185587132—3142
Triple negative breast neoplasmsD064726246319—194
Small cell lung carcinomaD055752255322—187
Head and neck neoplasmsD006258174810—166
Endometrial neoplasmsD016889EFO_0004230233013——59
Uterine cervical neoplasmsD002583152621—257
Esophageal neoplasmsD004938C1519336—253
NeuroblastomaD009447EFO_0000621102418—453
Ovarian epithelial carcinomaD00007721622266—148
Central nervous system neoplasmsD01654315267—547
Show 92 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471C611026———32
Stomach neoplasmsD013274EFO_0003897C161314———22
Pancreatic neoplasmsD010190EFO_0003860C2596——115
Hodgkin diseaseD006689C81911——114
CystadenocarcinomaD00353654——110
Follicular lymphomaD008224C8256——19
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.044——18
Male breast neoplasmsD01856744———8
Myeloid leukemia acuteD015470C92.033——17
B-cell chronic lymphocytic leukemiaD015451C91.144——17
Show 105 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colonic neoplasmsD003110C183————3
Multiple myelomaD009101C90.01———12
Renal insufficiencyD051437HP_0000083N192————2
NeutropeniaD009503D702————2
Vaginal neoplasmsD014625C522————2
Precancerous conditionsD0112302————2
Hematologic neoplasmsD0193371————1
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_00003401————1
Myeloid leukemia chronic-phaseD0154661————1
ThrombocytosisD013922D75.831————1
Show 28 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Immunoglobulin light-chain amyloidosisD000075363————11
Breast diseasesD001941N60-N65————11
OtotoxicityD000081015————11
SarcopeniaD055948EFO_1000653M62.84————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCARBOPLATIN
INNcarboplatin
Description
Carboplatin, sold under the trade name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer. This includes ovarian cancer, lung cancer, head and neck cancer, brain cancer, and neuroblastoma. It is used by injection into a vein.
Classification
Small molecule
Drug classantineoplastics (platinum derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
N.N.O=C([O-])C1(C(=O)[O-])CCC1.[Pt+2]
Identifiers
PDB—
CAS-ID41575-94-4
RxCUI40048
ChEMBL IDCHEMBL1351
ChEBI ID31355
PubChem CID10339178
DrugBankDB00958
UNII IDBG3F62OND5 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 66,140 documents
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Safety
Black-box Warning
Black-box warning for: Carboplatin, Paraplatin
Adverse Events
Top Adverse Reactions
Mock data
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63,855 adverse events reported
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