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Carbimazole
Carbimazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
H: Systemic hormonal preparations, excl. sex hormones and insulins
— H03: Thyroid therapy drugs
— H03B: Antithyroid preparations
— H03BB: Sulfur-containing imidazole derivatives, antithyroid preparations
— H03BB01: Carbimazole
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ThyrotoxicosisD013971E05——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HyperthyroidismD006980E05.9————11
Graves ophthalmopathyD049970EFO_1001466————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCARBIMAZOLE
INNcarbimazole
Description
Carbimazole is a member of the class of imidazoles that is methimazole in which the nitrogen bearing a hydrogen is converted into its ethoxycarbonyl derivative. A prodrug for methimazol, carbimazole is used for the treatment of hyperthyroidism. It has a role as a prodrug and an antithyroid drug. It is a carbamate ester and a member of 1,3-dihydroimidazole-2-thiones.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCOC(=O)n1ccn(C)c1=S
Identifiers
PDB—
CAS-ID22232-54-8
RxCUI2020
ChEMBL IDCHEMBL508102
ChEBI ID617099
PubChem CID31072
DrugBankDB00389
UNII ID8KQ660G60G (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,313 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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543 adverse events reported
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