Cantuzumab ravtansine
Cantuzumab ravtansine is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target mucin-1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | 1 | — | — | — | — | 1 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CANTUZUMAB RAVTANSINE |
| INN | cantuzumab ravtansine |
| Description | Cantuzumab Ravtansine (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies; maytansinoid derivatives |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 868747-45-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1742998 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB05594 |
| UNII ID | RNQ8JQ4R9P (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
MUC1
MUC1
Organism
Homo sapiens
Gene name
MUC1
Gene synonyms
PUM
NCBI Gene ID
Protein name
mucin-1
Protein synonyms
Breast carcinoma-associated antigen DF3, CA 15-3, Cancer antigen 15-3, Carcinoma-associated mucin, CD227, EMA, Episialin, H23 antigen, H23AG, KL-6, Krebs von den Lungen-6, mucin 1, transmembrane, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Uniprot ID
Mouse ortholog
Muc1 (17829)
mucin-1 (Q02496)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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