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Exparel, Posimir (bupivacaine) is a small molecule pharmaceutical. Bupivacaine was first approved as Exparel on 2011-10-28. It is used to treat postoperative pain in the USA. It has been approved in Europe to treat acute pain. It is known to target G protein-activated inward rectifier potassium channel 2, potassium voltage-gated channel subfamily D member 3, potassium voltage-gated channel subfamily A member 5, and sodium channel protein type 5 subunit alpha. Bupivacaine hydrochloride and epinephrine's patents are valid until 2041-01-22 (FDA).
Trade Name Exparel liposomal
Common Name Bupivacaine
Indication acute pain, postoperative pain
Drug Class Local anesthetics
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