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Bintrafusp alfa
Bintrafusp alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death 1 ligand 1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
57 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C80851——11
Non-small-cell lung carcinomaD002289361——7
Lung neoplasmsD008175C34.90251——6
CholangiocarcinomaD018281C22.1131——4
Biliary tract neoplasmsD001661C24.9—31——3
Gallbladder neoplasmsD005706EFO_0004606C23—21——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C5061———6
Uterine cervical neoplasmsD00258345———6
Triple negative breast neoplasmsD06472632———4
Anus neoplasmsD001005EFO_0003835C2134———4
Oropharyngeal neoplasmsD00995934———4
Prostatic neoplasmsD011471C6123———3
MelanomaD00854522———2
Squamous cell carcinoma of head and neckD00007719512———2
Renal cell carcinomaD00229222———2
SarcomaD01250912———2
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Urogenital neoplasmsD014565EFO_0003863D071————1
Ovarian neoplasmsD010051EFO_0003893C561————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Esophageal neoplasmsD004938C15————11
Squamous cell neoplasmsD018307————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBINTRAFUSP ALFA
INNbintrafusp alfa
Description
Bintrafusp alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death 1 ligand 1.
Classification
Protein
Drug classfusion proteins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL4298024
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDNW9K8C1JN3 (ChemIDplus, GSRS)
Target
Agency Approved
CD274
CD274
Organism
Homo sapiens
Gene name
CD274
Gene synonyms
B7H1, PDCD1L1, PDCD1LG1, PDL1
NCBI Gene ID
29126
Protein name
programmed cell death 1 ligand 1
Protein synonyms
B7 homolog 1, B7-H1, CD274, CD274 antigen, PDCD1 ligand 1
Uniprot ID
Q9NZQ7
Mouse ortholog
Cd274 (60533)
programmed cell death 1 ligand 1 (Q9EP73)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 357 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6 adverse events reported
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