Skip to content
Bezafibrate
Bezafibrate is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against peroxisome proliferator-activated receptor alpha.
Download report
Favorite
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
C10: Lipid modifying agents
C10A: Lipid modifying agents, plain
C10AB: Fibrates, lipid modifying drugs, plain
C10AB02: Bezafibrate
HCPCS
No data
Clinical
Clinical Trials
18 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypercholesterolemiaD006937HP_000312411
Acute coronary syndromeD054058EFO_000567211
Inferior wall myocardial infarctionD056989EFO_100098311
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Biliary liver cirrhosisD008105K74.3235
Sclerosing cholangitisD015209EFO_0004268K83.0122
CholestasisD002779K83.111
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 2 diabetes mellitusD003924EFO_0001360E1111
Bipolar disorderD001714EFO_0000289F30.911
Mitochondrial diseasesD028361EFO_000059111
Hemophilia bD002836D6711
Myelodysplastic syndromesD009190D4611
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypertriglyceridemiaD015228EFO_000421111
AdrenoleukodystrophyD000326Orphanet_43E71.5211
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameBEZAFIBRATE
INNbezafibrate
Description
Bezafibrate is a monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia. It has a role as a xenobiotic, an environmental contaminant, a geroprotector and an antilipemic drug. It is a monocarboxylic acid, an aromatic ether, a member of monochlorobenzenes and a monocarboxylic acid amide. It is functionally related to a propionic acid.
Classification
Small molecule
Drug classantihyperlipidemics (clofibrate type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O
Identifiers
PDB7BPZ
CAS-ID41859-67-0
RxCUI1525
ChEMBL IDCHEMBL264374
ChEBI ID47612
PubChem CID39042
DrugBankDB01393
UNII IDY9449Q51XH (ChemIDplus, GSRS)
Target
Agency Approved
PPARA
PPARA
Organism
Homo sapiens
Gene name
PPARA
Gene synonyms
NR1C1, PPAR
NCBI Gene ID
Protein name
peroxisome proliferator-activated receptor alpha
Protein synonyms
Nuclear receptor subfamily 1 group C member 1, peroxisome proliferative activated receptor, alpha
Uniprot ID
Mouse ortholog
Ppara (19013)
peroxisome proliferator-activated receptor alpha (P23204)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 3,948 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
427 adverse events reported
View more details