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Atracurium besylate
Tracrium (atracurium besylate) is a small molecule pharmaceutical. Atracurium besylate was first approved as Tracrium preservative free on 1983-11-23.
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Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Atracurium besylate
Tradename
Company
Number
Date
Products
TRACRIUMHospiraN-018831 DISCN1985-06-20
1 products, RLD
TRACRIUM PRESERVATIVE FREEHospiraN-018831 DISCN1983-11-23
1 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
atracurium besylateANDA2022-11-01
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
31 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postoperative painD010149G89.18——1113
AnesthesiaD000758———123
Neuromuscular blockadeD019148———112
Postoperative nausea and vomitingD020250EFO_0004888———112
Conduction anesthesiaD000765———1—1
Prostatic hyperplasiaD011470EFO_0000284N40———1—1
Retinal diseasesD012164HP_0000479H35.9———1—1
MyoclonusD009207HP_0001336G25.3———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PremedicationD011292—22——2
Intratracheal intubationD007442—22——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Radical mastectomyD01540911———1
Intraocular pressureD007429—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Colorectal neoplasmsD015179————11
Male breast neoplasmsD018567————11
Swine diseasesD013553————11
Urologic diseasesD014570N39.9————11
Lacrimal duct obstructionD007767————11
Inguinal herniaD006552HP_0000023K40————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameATRACURIUM BESYLATE
INNatracurium besilate
Description
Atracurium besylate is the bisbenzenesulfonate salt of atracurium. It has a role as a nicotinic antagonist and a muscle relaxant. It is a quaternary ammonium salt and an organosulfonate salt. It contains an atracurium.
Classification
Small molecule
Drug classquaternary ammonium derivatives: neuromuscular blocking agents
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]2(C)CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)cc1OC.O=S(=O)([O-])c1ccccc1.O=S(=O)([O-])c1ccccc1
Identifiers
PDB—
CAS-ID64228-81-5
RxCUI1219
ChEMBL IDCHEMBL1200527
ChEBI ID2915
PubChem CID47320
DrugBankDB00732
UNII ID40AX66P76P (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 308 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,477 adverse events reported
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