Praziquantel, (r)-
Praziquantel, (r)- is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
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Indications
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Agency Specific
FDA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
42 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schistosomiasis | D012552 | EFO_1001475 | B65 | 1 | 4 | 4 | 2 | 6 | 16 |
| Schistosomiasis mansoni | D012555 | EFO_1001420 | B65.1 | — | 2 | — | 2 | 1 | 5 |
| Helminthiasis | D006373 | EFO_1001342 | B65-B83 | — | — | — | 1 | 3 | 4 |
| Malaria | D008288 | EFO_0001068 | B54 | — | — | — | 1 | 3 | 4 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | 1 | 2 | 3 |
| Hiv | D006678 | O98.7 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 5 | — | 1 | — | — | 6 | ||
| Schistosoma mansoni | D012550 | NCBITaxon_6183 | — | 1 | 3 | — | 1 | 4 | |
| Schistosoma haematobium | D012548 | — | 1 | 2 | — | — | 2 | ||
| Neurocysticercosis | D020019 | — | 1 | 2 | — | — | 2 | ||
| Schistosomiasis haematobia | D012553 | EFO_0007530 | B65.0 | — | — | 1 | — | — | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | 1 | — | — | 1 |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schistosomiasis japonica | D012554 | EFO_1001419 | B65.2 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parasitic diseases | D010272 | EFO_0001067 | B88 | — | — | — | — | 2 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 2 | 2 |
| Taeniasis | D013622 | EFO_1001433 | B68 | — | — | — | — | 1 | 1 |
| Schistosoma | D012547 | — | — | — | — | 1 | 1 | ||
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | |
| Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | — | — | 1 | 1 |
| Opportunistic infections | D009894 | — | — | — | — | 1 | 1 | ||
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| Oxidative stress | D018384 | EFO_1001905 | — | — | — | — | 1 | 1 | |
| Hematuria | D006417 | HP_0000790 | R31 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PRAZIQUANTEL, (R)- |
| INN | arpraziquantel |
| Description | 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one is a member of isoquinolines. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3[C@@H]2C1 |
Identifiers
| PDB | — |
| CAS-ID | 55268-74-1 |
| RxCUI | 8628 |
| ChEMBL ID | CHEMBL1235551 |
| ChEBI ID | — |
| PubChem CID | 4891 |
| DrugBank | DB01058 |
| UNII ID | WF15T5925V (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
0 adverse events reported
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