Anacetrapib
Anacetrapib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
16 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dyslipidemias | D050171 | HP_0003119 | 3 | 1 | 1 | — | — | 5 | |
| Hypercholesterolemia | D006937 | HP_0003124 | 1 | 1 | 2 | — | — | 4 | |
| Hyperlipoproteinemia type ii | D006938 | EFO_0004911 | E78.00 | — | — | 2 | — | — | 2 |
| Coronary disease | D003327 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperlipoproteinemia type v | D006954 | Orphanet_70470 | E78.3 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ANACETRAPIB |
| INN | anacetrapib |
| Description | Anacetrapib is a CETP inhibitor which was being developed to treat elevated cholesterol levels in an effort to prevent cardiovascular disease. In 2017 its development was abandoned by Merck.
|
| Classification | Small molecule |
| Drug class | cholesterol ester transfer protein inhibitors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc(F)c(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C |
Identifiers
| PDB | — |
| CAS-ID | 875446-37-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1800807 |
| ChEBI ID | — |
| PubChem CID | 11556427 |
| DrugBank | DB06630 |
| UNII ID | P7T269PR6S (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
PubMed Central
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Additional graphs summarizing 841 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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1 adverse events reported
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