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Elavil (amitriptyline) is a small molecule pharmaceutical. Amitriptyline was first approved as Elavil on 1982-01-01. It is used to treat depressive disorder, pain, and psychotic affective disorders in the USA. The pharmaceutical is active against histamine H1 receptor, sodium-dependent noradrenaline transporter, muscarinic acetylcholine receptor M5, muscarinic acetylcholine receptor M2, muscarinic acetylcholine receptor M4, muscarinic acetylcholine receptor M1, sodium-dependent serotonin transporter, and muscarinic acetylcholine receptor M3. In addition, it is known to target 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 7, 5-hydroxytryptamine receptor 2C, lysophosphatidic acid receptor 1, G protein-activated inward rectifier potassium channel 4, G protein-activated inward rectifier potassium channel 2, and alpha-1-acid glycoprotein 2.
Trade Name Elavil
Common Name Amitriptyline
Indication depressive disorder, pain, psychotic affective disorders
Drug Class Antidepressants (dibenzo[a,d]cycloheptane derivatives)
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