Alverine
Alverine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
12 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | 1 | 4 | 1 | 6 |
Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Urinary bladder neoplasms | D001749 | C67 | — | — | — | — | 1 | 1 | |
| Urinary incontinence | D014549 | HP_0000020 | R32 | — | — | — | — | 1 | 1 |
| Postcholecystectomy syndrome | D017562 | EFO_1001117 | K91.5 | — | — | — | — | 1 | 1 |
| Lactose intolerance | D007787 | E73 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ALVERINE |
| INN | alverine |
| Description | Alverine is a tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome. It has a role as an antispasmodic drug. It is a conjugate base of an alverine(1+). |
| Classification | Small molecule |
| Drug class | spasmolytic agents (papaverine type) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCN(CCCc1ccccc1)CCCc1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 150-59-4 |
| RxCUI | 17627 |
| ChEMBL ID | CHEMBL253371 |
| ChEBI ID | 518413 |
| PubChem CID | 3678 |
| DrugBank | DB01616 |
| UNII ID | 46TIR1560O (ChemIDplus, GSRS) |
Target
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Additional graphs summarizing 177 documents
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Safety
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Adverse Events
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1,485 adverse events reported
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