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Alseroxylon
Rautensin, Rauwiloid (alseroxylon) is a small molecule pharmaceutical. Alseroxylon was first approved as Rauwiloid on 1982-01-01.
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Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Alseroxylon
Tradename
Company
Number
Date
Products
RAUWILOID3MN-008867 DISCN1982-01-01
1 products
RAUTENSINNovartisN-009215 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
170 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
GoutD006073EFO_0004274M10211127436
HyperuricemiaD0334611744420
Chronic renal insufficiencyD051436N1833—129
Heart failureD006333EFO_0003144I501513—8
Cardiovascular diseasesD002318EFO_0000319I984121—7
HypertensionD006973EFO_0000537I101321—5
Kidney calculiD007669EFO_0004253N20.0—1—2—3
Diabetic nephropathiesD003928EFO_0000401——1113
ManiaD000087122F30——12—3
Left ventricular hypertrophyD017379EFO_0003896———3—3
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.0242—18
Non-hodgkin lymphomaD008228C85.9—22—15
ObesityD009765EFO_0001073E66.9—12——3
Type 2 diabetes mellitusD003924EFO_0001360E11—12——3
PrehypertensionD058246—21——2
Hiv infectionsD015658EFO_0000764B20——1—12
NeoplasmsD009369C80—11——2
Tumor lysis syndromeD015275E88.3——2——2
Coronary artery diseaseD003324I25.1——1—12
Heart diseasesD006331EFO_0003777I51.9111——2
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938C9526———8
Myelodysplastic syndromesD009190D4623——16
LymphomaD008223C85.923———5
Multiple myelomaD009101C90.013———4
Myeloid leukemia acuteD015470C92.0—3——14
Obstructive sleep apneaD020181EFO_0003918G47.33—1——23
Plasma cell neoplasmsD05421921———3
B-cell chronic lymphocytic leukemiaD015451C91.1—2———2
Burkitt lymphomaD002051C83.7—2———2
Metabolic syndromeD024821EFO_0000195E88.81—2———2
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—6————6
Heart disease risk factorsD0000827423————3
VasoconstrictionD0146612————2
Myeloproliferative disordersD009196D47.11————1
Graft vs host diseaseD006086D89.811————1
VasodilationD0146641————1
TuberculosisD014376EFO_0000774A15-A191————1
Inflammatory bowel diseasesD015212EFO_00037671————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cutaneous leishmaniasisD016773B55.1————22
Prediabetic stateD011236EFO_1001121R73.03————11
Insulin resistanceD007333EFO_0002614————11
Endoscopic retrograde cholangiopancreatographyD002760————11
Iga glomerulonephritisD005922EFO_0004194————11
Fetal growth retardationD005317EFO_0000495————11
Non-alcoholic fatty liver diseaseD065626EFO_0003095K75.81————11
Chronic kidney disease-mineral and bone disorderD012080EFO_1001152N25.0————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameALSEROXYLON
INN—
Description
Alseroxylon (Rautensin, Rauwiloid) is a norepinephrine reuptake inhibitor that has been investigated in the treatment of hypertension and angina pectoris and as a sedative in psychoses. It was at one time approved for use in the United States, but has since been discontinued.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID8001-95-4
RxCUI599
ChEMBL IDCHEMBL1201454
ChEBI ID—
PubChem CID—
DrugBankDB00386
UNII ID—
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 62 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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18,299 adverse events reported
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