Sodium Citrate

Status : approved

Therapeutic Classification

IRRIGATING SOLUTIONS

BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS

Used

For use only with automated apheresis devices in the collection of human plasma or in performing therapeutic plasma exchange procedures.

Dosage

Form Route Strength
Solution 0-unassigned 4 g
Liquid intravenous 4 %
Powder oral 3.5 g
Powder (effervescent) oral 1.19 g
Powder oral 2.65 g
Liquid oral 26.1 mg
Syrup oral 5 mg
Syrup oral 1 mg
Liquid oral 640 mg
Powder oral 2.645 g
Solution intravenous 10 g/250mL

Chemical Classification

This compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.

Tricarboxylic acids and derivatives

Organic compounds

Organic acids and derivatives

Carboxylic acids and derivatives

Tricarboxylic acids and derivatives

Brands

name Dosage form Country
Anticoagulant Sod Citrate Soltn 4gm/100ml solution Canada
Anticoagulant Sodium Citrate solution US
Anticoagulant Sodium Citrate Sol 4% USP liquid Canada
Anticoagulant Sodium Citrate Solution USP solution Canada
Bromo Seltzer powder Canada
Citrocarbonate Eff Pws powder (effervescent) Canada
Lemon Eno 2650mg/pck powder Canada
Lytren Rhs Liq liquid Canada
Metrate syrup Canada
Neo Tuss Syr syrup Canada
Oracit liquid Canada
Orange Eno 2645mg/pck powder Canada
Sodium Citrate solution US
Vito Bronches Sirop syrup Canada

Drug Drug Interactions

  •  Aluminum hydroxide  : Citric Acid Derivatives may increase the absorption of Aluminum hydroxide.

Calculated Property

kind Value Source
logP -0.55 ALOGPS
logS -0.54 ALOGPS
Water Solubility 7.37e+01 g/l ALOGPS
logP -1.3 ChemAxon
IUPAC Name trisodium 2-hydroxypropane-1,2,3-tricarboxylate ChemAxon
Traditional IUPAC Name trisodium citrate ChemAxon
Molecular Weight 258.068 ChemAxon
Monoisotopic Weight 257.97283534 ChemAxon
SMILES [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O ChemAxon
Molecular Formula C6H5Na3O7 ChemAxon
InChI InChI=1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 ChemAxon
InChIKey HRXKRNGNAMMEHJ-UHFFFAOYSA-K ChemAxon
Polar Surface Area (PSA) 140.62 ChemAxon
Refractivity 68.14 ChemAxon
Polarizability 14.23 ChemAxon
Rotatable Bond Count 5 ChemAxon
H Bond Acceptor Count 7 ChemAxon
H Bond Donor Count 1 ChemAxon
pKa (strongest acidic) 3.05 ChemAxon
pKa (strongest basic) -4.2 ChemAxon
Physiological Charge -3 ChemAxon
Number of Rings 0 ChemAxon
Bioavailability 1 ChemAxon
Rule of Five 1 ChemAxon
Ghose Filter 0 ChemAxon
MDDR-Like Rule 0 ChemAxon