Ibuproxam

Status : withdrawn

Therapeutic Classification

ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS

MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS

Description

Ibuproxam is a non steroidal anti-inflammatory drug (NSAID).

Chemical Classification

Calculated Property

kind Value Source
logP 3.17 ALOGPS
logS -3.5 ALOGPS
Water Solubility 6.82e-02 g/l ALOGPS
logP 3.85 ChemAxon
IUPAC Name N-hydroxy2-[4-(2-methylpropyl)phenyl]propanimidic acid ChemAxon
Traditional IUPAC Name ibuproxam ChemAxon
Molecular Weight 221.2955 ChemAxon
Monoisotopic Weight 221.141578857 ChemAxon
SMILES CC(C)CC1=CC=C(C=C1)C(C)C(O)=NO ChemAxon
Molecular Formula C13H19NO2 ChemAxon
InChI InChI=1/C13H19NO2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(15)14-16/h4-7,9-10,16H,8H2,1-3H3,(H,14,15) ChemAxon
InChIKey InChIKey=BYPIURIATSUHDW-UHFFFAOYNA-N ChemAxon
Polar Surface Area (PSA) 52.82 ChemAxon
Refractivity 64.84 ChemAxon
Polarizability 25.41 ChemAxon
Rotatable Bond Count 4 ChemAxon
H Bond Acceptor Count 3 ChemAxon
H Bond Donor Count 2 ChemAxon
pKa (strongest acidic) 6.67 ChemAxon
pKa (strongest basic) 1.07 ChemAxon
Physiological Charge -1 ChemAxon
Number of Rings 1 ChemAxon
Bioavailability 1 ChemAxon
Rule of Five 1 ChemAxon
Ghose Filter 1 ChemAxon
MDDR-Like Rule 0 ChemAxon