2,6-Diaminopimelic Acid

Status : experimental

Chemical Classification

This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.

L-alpha-amino acids

Organic compounds

Organic acids and derivatives

Carboxylic acids and derivatives

Amino acids, peptides, and analogues

Calculated Property

kind Value Source
logP -4.1 ALOGPS
logS -1.1 ALOGPS
Water Solubility 1.41e+01 g/l ALOGPS
logP -5.5 ChemAxon
IUPAC Name (2S,6S)-2,6-diaminoheptanedioic acid ChemAxon
Traditional IUPAC Name diamino-pimelic acid ChemAxon
Molecular Weight 190.1971 ChemAxon
Monoisotopic Weight 190.095356946 ChemAxon
SMILES N[C@@H](CCC[C@H](N)C(O)=O)C(O)=O ChemAxon
Molecular Formula C7H14N2O4 ChemAxon
InChI InChI=1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1 ChemAxon
InChIKey InChIKey=GMKMEZVLHJARHF-WHFBIAKZSA-N ChemAxon
Polar Surface Area (PSA) 126.64 ChemAxon
Refractivity 43.64 ChemAxon
Polarizability 18.93 ChemAxon
Rotatable Bond Count 6 ChemAxon
H Bond Acceptor Count 6 ChemAxon
H Bond Donor Count 4 ChemAxon
pKa (strongest acidic) 1.85 ChemAxon
pKa (strongest basic) 9.83 ChemAxon
Physiological Charge 0 ChemAxon
Number of Rings 0 ChemAxon
Bioavailability 1 ChemAxon
Rule of Five 1 ChemAxon
Ghose Filter 0 ChemAxon
MDDR-Like Rule 0 ChemAxon

Target within organism

  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase : in Escherichia coli (strain K12)
  • Meso-diaminopimelate D-dehydrogenase : in Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)