19-Nor-5-androstenedione

Synonyms :
(8R,9S,10R,13S,14S)-13-Methyl-1,2,4,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione, (8R,9S,10R,13S,14S)-13-Methyl-1,2,4,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-quinone, 3β,17β-dihydroxyestr-5-ene and 3α,17β-dihydroxyestr-5-ene, estr-5-en-3,17-dione

Status : experimental

Category

Steroids

Description

19-Nor-5-andorstenedione is a prohormone which has the potential to affect bodily levels of testosterone once metabolized in vivo. It is regulated in the United States as a schedule III controlled substance, and prohibited by the World Anti-Doping Agency for use in competitive sports.

Mechanism Of Action

It is believed that 19-Nor-5-andorstenedione may be metabolized in the body to produce a metabolite which can activate the androgen receptor, similar to testosterone. However, androgen receptor activation is likely less than that of testosterone or dihydrotestosterone.

Toxic Effect

Because 19-Nor-5-androstenedione is metabolically related to
other controlled anabolic steroids, it is likely to have similar adverse health effects such as liver, heart and skin problems, hormonal disruptions, stunted growth,
and psychological effects such as rage and depression.

Chemical Classification

Chemical Name

(8R,9S,10R,13S,14S)-13-Methyl-1,2,4,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione

Calculated Property

kind Value Source

Affected organism

Humans and other mammals